Many medical experts consider the influenza virus (cause of the flu) to be the most dangerous virus in the world. Several times in past history, this virus has been responsible for killing huge numbers of people within a 1 to 2 year period. As an example, the Spanish flu (type A(H1N1)) of 1918-19 killed about 500,000 people in the U.S. and at least 20 million people worldwide. In 1957-58, the Asian flu (type A(H2N2)) resulted in 70,000 deaths in the US and in 1968-69, the Hong-Kong flu (type (A(H3N2)) killed 34,000 in the U.S.

What is the Flu?

Let’s pause here and take a moment to get a clearer picture of what the flu really is. Terminology and language can be fickle and non-specific masters, and so the common day-to-day use of the term flu has evolved to often encompass anything from a common cold to a true flu.

The stomach flu is another misleading term, often used to describe a gastrointestinal illness (the stomach flu is usually not even caused by a virus but by other microorganisms). So, the first critical point to understand is that a flu is not a common cold or a stomach infection.

When researchers, or doctors speak of the flu, they are being very specific and mean an infection by the influenza virus. Epidemic influenza is divided into type A and type B. The most common presentation of influenza includes a fever (usually 100-103 degrees F in adults), respiratory symptoms (such as cough, sore throat, runny or stuffy nose), headache, muscle aches, and often extreme fatigue. So, the second key point is that public health officials and doctors mean influenza virus when they use the term flu.

The year-in, year-out flu can be deadly (in an average year, influenza is associated with about 20,000 deaths), especially for the elderly, immuno-compromised, or those who have an existing condition, such as asthma, diabetes or heart disease. Even for those of us who are in generally good health, the flu can still really “take the wind out of our sails”, causing us to feel miserable for several days to a week or two.

Currently there are three main variants of the flu circulating (two types “A” and one type “B”). The type A variants are the “Hong Kong” type A(H3N2) virus and its relatives (responsible for about 400,000 deaths in the United States since 1968 (90% of which are among the elderly), and distant relatives of the “Spanish Flu”, type A(H1N1). The “H” and “N” refer to viral proteins called haemagglutinin (H) and the neuraminidase (N) (more on this in a bit).

Some medical and public health experts believe it is only a matter of time (in fact they think we are overdue) before a new pandemic (worldwide epidemic) of the flu occurs, killing many, many people.

Why has the flu been able to kill such large numbers of people so quickly in the past? 

I am going to oversimplify here, but follow along.

The flu virus is able to mutate or change over time, allowing it to reinfect you year after year. Usually this is a slow and very gradual process (both type A and B influenza virus can change in this manner). As an example, if you were exposed to last year’s flu virus, your immune system would have created a very specific memory of how to effectively deal with the virus. A new exposure to the same virus would not now be a problem. Since the virus changes a slight amount each year, last years immune memory will partially, but not completely protect you from this year’s influenza infection. Think of it in terms of not seeing a friend for a long while…they will obviously look a bit different, so it might take a moment for you to recognize them and remember their name. However, once this moment passes and you remember the name, you now have a clear idea of how to greet them However, every once in a while, the type A flu virus (the type B does not change in this manner) will have a dramatic and abrupt change to either its haemagglutinin (H) and/or neuraminidase (N) proteins. This results in a new strain of the virus, which is not recognized as something your immune system dealt with in the past. It would be as if a new person moved into your town; you have no information in your memory to identify them as your friend and no idea of the name. In the years that the flu virus became a worldwide epidemic and killed into the millions of people, the flu virus changed in this manner.

Blood type and the flu?

Quite a few different researchers have investigated blood type and influenza. The volume of research alone is almost enough to suggest strong blood type connections, but let’s look at the research just to be sure.

After exposure to the influenza virus, an immune process termed seroconversionshould occur. This means that your immune system should be producing antibodies against the influenza virus. Researchers have found that after circulation of influenza A (type (H1N1) and (H3N2)) and influenza B viruses, the immune response (as measured in a rise in antihaemagglutinin antibodies against the virus) differ along blood type lines.

The following generalized immune observations apply:

Blood type A: Overall has a great ability to generate a quick and substantial antibody response against influenza type A(H1N1) and especially A(H3N2). Their antibody response against influenza B is not quite as dramatic.

Blood type AB: Relatively poor ability to generate high antibody levels against any of the influenza viruses.

Blood type B: Reasonable, but not great ability to generate an antibody response against influenza A(H1N1). Slowest (it can take them 3-5 months) and weakest ability to generate antibodies against influenza A(H3N2) of any blood type. Against influenza B virus, blood type B has a significant advantage and responds differently from either blood group A or O. The blood type B immune response happens much earlier and persists longer.

Blood type O: Relatively decent ability to generate antibody response against influenza A(H1N1) and A(H3N2) viruses. Antibody response against influenza B is not as dramatic as blood type B.

Some researchers have hypothesized that one explanation for the typical emergence of the new epidemic strains of influenza in Asia is connected to blood type (and the relatively high proportion of type B blood found in Asia). It seems that blood type B has a genetic predisposition to latent (chronic) persistence of influenza A virus (especially A(H3N2) “Hong Kong” variants). Often, the influenza virus antigen can still be found in healthy type B individuals as much as 5 months after a flu. This means that although they might not have symptoms, they are providing a safe harbor for the virus.

With these differences in immune responses, we would expect to see differences in susceptibility to and severity of influenza infection between the different blood types…and indeed we do. What we find is that the susceptibility to influenza changes based upon your blood type and the properties of the circulating strains of influenza virus.

Looking at influenza A as a whole, the following blood type generalities exist. People with blood type B are going to be much more susceptible to infection during times when new antigenic variants and serotype’s of influenza virus appear. This is actually particularly bad news for B’s and AB’s, since this is the type of influenza A virus change that results in widespread flu pandemics. Blood type O individuals tend to be susceptible to influenza infection at the period of the circulation of virulent strains (so in years when the flu is making people feel really sick, type O will be hit the hardest). Type A’s are the lucky ones when it comes to influenza A; they have a generalized susceptibility to the less virulent strains of influenza A.

Overall, influenza is probably most problematic year to year for Type AB’s. In general, they are more sensitive to infection by both influenza A and B than the other blood types. They are affected by these viruses earlier and more severely than those with the other blood groups (and they need to be extra cautious regarding an abrupt change in the influenza A virus as well) . Blood type B is most severely affected when the influenza A(H3N2) (this is the “Hong Kong” variety and its relatives) is in circulation; has relatively little difficulty with influenza B and has to be very concerned about an abrupt change in the influenza A strains. Type O gets less influenza A(H1N1) and more A(H3N2). Type A blood indirectly offers relative protection against both strains of influenza A.

Will the flu shot protect me?

Does the flu shot protect the blood types differently? Well, what the research shows is that all blood types will have similar seroconversion frequencies to both the live attenuated and killed subunit vaccines after the administration of TWO doses. But after only ONE dose of the live vaccine, blood type A is much more likely than the other blood types to seroconvert. The lesson to be learned here is that blood types B, AB and O really should probably get two doses of the live vaccine for best results (most type A’s can probably get away with just one dose). With the killed subunit vaccine, type O produces the greatest anti-haemagglutinin antibody response. Again two doses generally places the blood types on equal ground.

In addition to the blood type information, remember the following. This year’s flu shot is made from the most common flu viruses in circulation last year. So, in most years, when the virus changes only a tiny bit from last year, the flu shot will offer some protection.

Note: There are many people nevertheless who benefit significantly from the flu shot including elderly, chronically ill, and immuno-compromised individuals. For more information on who should receive this vaccination it is advised that you contact a physician or the department of public health.

Essentially, the effectiveness of the flu shot is always going to be dependent on how closely the vaccine matches the strain of flu virus in current circulation. So, if the virus changes dramatically from last year (as it did in the pandemic years), the flu shot will be of little to no use, because, in essence, it is not providing you with any one who knows this new person in town. So a key point then with regards to the flu shot is that it offers protection in most years, but probably not from a pandemic flu.

Antivirals and the flu

Amantadine and rimantadine are chemically related drugs that interfere with the replication cycle of influenza type A viruses (they are not effective against influenza type B). They both offer a decent degree of protection against infection if taken daily during flu season; however, cost, compliance, and side-effects limit this type of use for most people.

Amantadine and rimantadine are also useful in treatment of the flu; able to reduce the severity and shorten the duration of influenza A if given within the first 48 hours. One huge drawback with these antiviral’s is that they result in Amantadine- and rimantadine-resistant influenza A viruses when they are used for treatment (a very poor long-term strategy resulting essentially in a possible ineffectiveness of these drugs when you might need them the most for a severe or life-threatening flu).

Zanamivir and Neuraminidase Inhibitors.

Zanamivir was the first in a new class of drugs known as selective viral neuraminidase inhibitors. And, if in fact the old saying that “imitation is the most sincere form of flattery” holds true, this type of drug must hold tremendous promise. Pharmaceutical and biotechnology companies (including one of the industry giants—Hoffman La Roche) have quickly jumped on the neuraminidase band-wagon and are now either planning a launch or are in the process of developing their own neuraminidase inhibitors.

The reason Zanamivir is such a promising development is that in humans it not only prevents influenza infection, but also reduces the duration and intensity of the typical symptoms if given within the first 30 hours during an influenza infection. Let’s take a moment here to discuss haemagglutinins and neuraminidase in the context of influenza (remember these are the H and N in the A(H1N1) and A(H3N2) strains).

The influenza virus forms haemagglutinins (essentially protein spikes) which release an enzyme called neuraminidase in order to spread to new cells and propagate the infection. From a biochemistry perspective, neuraminidase is an enzyme that cleaves terminal sialic acid residues from glycoconjugates (Does the term glycoconjugate remind you of anything? It should, because the antigens on your cells like your ABO marker are glycoconjugates). By cleaving off the sialic acid sugar, the virus can escape from infected cells, spread to new cells, and make the mucus you produce in response to an infection less effective (yes, the runny nose and mucus you produce in response to a cold or flu are actually part of your body’s defense strategy).

It was assumed that an ability to inhibit neuraminidase would be a useful medical intervention for treating (and maybe preventing) the flu. So far in the trials on Zanamivir, this assumption appears to be true. The biggest disadvantage with Zanamivir is that it is not well absorbed orally, so must be given by inhalation. Its use might also be limited by its cost. So far, researchers claim that resistance of the virus to the drug has been only rarely observed (but remains a possible area of concern).

Elderberry and the flu

So where does elderberry fit in this portrait of the flu. I have mentioned it was used historically, but does it work? In experiments, elderberry actually does inhibit replication of all strains of human influenza.

In an actual placebo-controlled, double blind study (the scientific gold-standard so to speak) an extract of elderberry fruit has been shown to be effective for treating influenza B. What this research showed was that people using the elderberry extract got better much quicker (more than 70% were better after 2 days and over 90% of people completely resolved the infection within 3 days). In contrast, the people given a placebo often needed as much as 6 days to feel well.

Why does elderberry work? Well, the researchers found two reasons really. People taking the elderberry were able to produce higher anti-haemagglutination titers to influenza B (meaning their immune system essentially performed better and they now have a higher level of recognition should this flu return). And, elderberry inhibits neuraminidase (yes, that is the same neuraminidase that scientists are spending millions of dollars designing drugs against). (Editor’s note: Zanamivir to an extent duplicates this neuraminidase blocking ability of elderberry, but does not appear to have elderberry’s beneficial impact on the immune system).

An important question that has not been answered yet is…will elderberry work as well against influenza A strains? I don’t have a definitive answer for you on this yet, but based upon its method of action, its in vitro ability, and my clinical observations, the answer is probably yes. Our patients taking the elderberry, blueberry, cherry and apple concentrate mixture, seemed to pass easily through this past flu season. The one word of caution I leave you with is that when it comes to daily use of elderberry, more is not always better. Large doses will lead to nausea. If you are trying to avoid a flu a small amount daily might help. I recommend elderberry especially for type B’s and AB’s because of their general susceptibility to the virus. For treatment we use 2 tablespoons 3-4 times daily for adults and less for children depending upon their body weight.

So, the final key point is…next flu season remember your friendly elderberry.

REFERENCES

1. Naikhin AN, Katorgina LG, Tsaritsyna IM, et al. Indicators of collective immunity to influenza depending on the blood group and sex of the population. Vopr Virusol 1989 Jul-Aug;34(4):419-23 [Article in Russian]
2. Aho K, Pyhala R, Visakorpi R. ABO associated genetic determinant in H1N1 influenza. Tissue Antigens 1980 Oct;16(4):310-3
3. Lebiush M, Rannon L, Kark JD. The relationship between epidemic influenza (A(H1N1) and ABO blood group. J Hyg (Lond) 1981 Aug;87(1):139-46
4. Sominina AA, Tsubalova LM, Karpova LS, et al. Genetic predisposition to latent influenza A virus in children with blood type B(III) as a possible cause of new epidemiologic strains in the countries of South-Eastern Asia. Vestn Ross Akad Med Nauk 1994;(9):21-4 [Article in Russian]
5. Fedorova GI, Slepushkin AN, Popova NS, et al. Correlations of the antigenic specificity of human blood with the levels of antihemagglutinins to influenza viruses. Vopr Virusol 1983 Jan-Feb;28(1):54-7 [Article in Russian]
6. Mackenzie JS, Fimmel PJ. The effect of ABO blood groups on the incidence of epidemic influenza and on the response to live attenuated and detergent split influenza virus vaccines. J Hyg (Lond) 1978 Feb;80(1):21-30
7. Mackenzie JS, Wetherall JD, Fimmel PJ, et al. Host factors and susceptibility to influenza A infection: the effect of ABO blood groups and HL-A antigens. Dev Biol Stand 1977 Jun 1-3;39:355-62
8. Frolov VK, Sokhin AA, Sotnik AY, et al. Polymorphism of human blood groups and incidence of influenza A/Hong Kong (H3N2). Acta Virol 1975 Sep;19(5):406-12
9. Karpova LS, Popova TL, Oleinikova EV, et al. Significance of persons with different blood groups in the influenza type A epidemic process. Zh Mikrobiol Epidemiol Immunobiol 1982;(11):86-91 [Article in Russian]
10. Waghorn SL, Goa KL. Zanamivir. Drugs 1998;55:721-25
11. Zakay-Jones Z, Varsano N, Zlotnik M, et al. Inhibition of several strains of influenza virus in vitro and reduction of symptoms by an elderberry extract (Sambucus nigra L.) during an outbreak of influenza B Panama

In an actual placebo-controlled, double blind study (the scientific gold-standard so to speak) an extract of elderberry fruit has been shown to be effective for treating influenza B. What this research showed was that people using the elderberry extract got better much quicker (more than 70% were better after 2 days and over 90% of people completely resolved the infection within 3 days). In contrast, the people given a placebo often needed as much as 6 days to feel well.

Why does elderberry work? Well, the researchers found two reasons really. People taking the elderberry were able to produce higher anti-haemagglutination titers to influenza B (meaning their immune system essentially performed better and they now have a higher level of recognition should this “flu” return). And, elderberry inhibits neuraminidase (yes, that is the same neuraminidase that scientists are spending millions of dollars designing drugs against).

An important question that has not been answered yet is…will elderberry work as well against influenza A strains? I don’t have a definitive answer for you on this yet, but based upon its method of action, its in vitro ability, and my clinical observations, the answer is probably yes. Our patients taking the elderberry, blueberry, cherry and apple concentrate mixture, seemed to pass easily through this past “flu” season.

The one word of caution I leave you with is that when it comes to daily use of elderberry, more is not always better. Large doses will lead to nausea. If you are trying to avoid a “flu” a small amount daily might help. I recommend elderberry especially for type B’s and AB’s because of their general susceptibility to the virus. For treatment we use 2 tablespoons 3-4 times daily for adults and less for children depending upon their body weight.

So, the final key point is…next “flu” season remember your friendly elderberry!

Source:  Dr. D’Adamo’s October 2010 Newsletter.

• We all know that immunity begins in our gut. By eating foods that are right for your type, you are taking the most important step to staying healthy. Step up your consumption of beneficial foods and remove any foods to be avoided  from your diet.
• Stress lowers immunity. We can’t completely avoid stress, but take a few moments to slow down – find 10 minutes a day to just sit and close your eyes, do some deep breathing or meditation.
• Exercise boosts immunity! Find an exercise that is right for you and stick with it. I love going for a brisk walk in the cool fall evenings as the sun is setting, it’s a great way to wind down the day and enjoy the beauty of the season.
• Avoid refined sugars and saturated fats. Although you may be eating right for your type, sometimes these find a way of sneaking into our diet – be vigilant.
• Take a quality vitamin and multimineral supplement and a proven immune-enhancing product like ARA or ProBerry.
• Follow good cough/sneeze etiquette. Wash your hands frequently, and avoid touching your face.

Your immune system, when working properly, has a remarkable ability to fight off the flu and colds. Even if an infection does gain a foothold, it’s usually just a matter of time before your immune system mounts an effective counter attack!

Your immune system, when working properly, has a remarkable ability to fight off the flu and colds. Even if an infection does gain a foothold, it’s usually just a matter of time before your immune system mounts an effective counter attack!

• Source: Dr.Ann Quasarano’s October 2010 Newsletter

I’ve often wondered why some people retain their mental acuity well into their senior years and others seem to experience a decline in mental function in their forties and fifties. Until recently, scientists believed that the answer lay solely in genetics and that little could be done to control the timing and rate of decline. But according to some new studies, developmental and environmental factors could be even more important.

Scientists have isolated a number of factors that contribute to premature aging and brain deterioration. These include: Mitochondrial damage, impaired circulation, hormonal deficiency, chronic stress, nitric oxide impairment, injury, tumors, and nutrient deficiency.

As your reference, Dr. D’Adamo has identified brain power superfoods that provide the maximum nutritional support to fight many of the conditions associated with aging. Below are the top 12 Brain Power Super Foods for each blood type.

Source:

• Dr. D’Adamo’s  September Newsletter

(This part is continuation of the previous article)

The soluble forms of fiber have value in control of blood cholesterol and blood sugar. Fruits, vegetables, beans, and oat bran are good sources of these forms of fiber.

The soluble fibers don’t lower blood cholesterol nearly as much as the cholesterol’s sources raise it. But a diet rich in fruits and vegetables has a mild cholesterol-lowering effect, thanks to the fiber. Lower blood cholesterol, of course, means lower rates of heart disease.

These soluble forms of fiber have also revolutionized the treatment of diabetes. New research has shown that a high-fiber diet helps diabetics control their blood sugar better than the diets used in the past. Their insulin requirements often drop on a high-fiber diet. Changes in insulin doses should be made only on a doctor’s instructions.

Fiber’s ability to keep the blood sugar under control may very well help people who do not have diabetes. A low-fiber meal can cause the blood sugar level to rise quickly, then drop abruptly. Headaches, hunger, and irritability can set in as a result.

But fiber can guard against these symptoms by preventing sharp swings in the blood sugar level.

How to Estimate Fiber Content?

If you want to estimate your fiber intake, consult the chart that follow. This chart gives the total fiber content of foods.

Total Fiber Content of Foods

(Soluble and Insoluble Fiber)

Unless otherwise indicated, all values for vegetables reflect fiber content of the cooked product. Analyzes of fiber content by James W. Anderson, High Carbohydrate and Fiber Research Foundation, Lexington, Kentucky.

Find the next powerful charts in the following article:

• Estimate Your Fiber Intake

( continuation of the previous article )

Scientists believe that we may be able to adapt to high-fiber diets. But this is not known for sure. It is speculation based on a handful of studies.

The effect of fiber on minerals varies among the different types. Here is what scientists think based on current knowledge:

• Iron nutrition probably won’t be affected by eating more fiber.
• Fiber probably will decrease absorption of zinc and copper.
• If zinc and copper intake is good, the decrease in absorption probably will not create any problems.

Whole grains contain more zinc and copper than refined grains, so this may offset any loss of these minerals resulting from the fiber. But until we know this for a fact, I feel it’s best to take a moderate rather than extreme approach to the fiber content of your diet.

Another Mineral-Robber

Fiber is not the only substances in whole grain foods that can bind to minerals. Whole grains also contain phytic acid, which can also tie up minerals. Nutritionists also refer to phytic acid as phytate.

Fortunately, we now know that yeast can destroy phytate. This means that it should not be a problem in whole grain breads made with yeast. Nutritionists believe that phytate is rarely a problem, except among people eating enormous amounts of unleavened bread. Few, if any, of us eat such a diet.

Fighting Fat with Fiber

If you’re weight watcher, you probably remember the ‘starch blockers’ that came out in 1982. The too-good-to-be true claims were just that. The pills landed more than two dozen people in the hospital. The FDA had its hands full getting the stuff off the market.

Well, fiber may be the only starch blocker that doesn’t make us sick.

Nutritionists have long known that fiber blocks the absorption of some of the calories in food. It not only blocks the calories from carbohydrates; it takes on protein, fat, and carbohydrate  pretty much equally. Studies show that people absorb 1% to 3% fewer calories when eating a high-fiber diet.

Sound like a fantasy? It is not. Most of us gain weight slowly, at the rate of an extra pound or two per year. For a woman needing 100 calories a day, a 1% fall in calories absorbed would mean a loss of two pounds per year. A 3% reduction in calories absorbed translates into 6 fewer pounds per year.

There’s only one catch. These findings come from short-term studies. No one knows whether the body will adapt to a high-fiber diet so that eventually just as many calories are absorbed.

Fiber researchers have reported getting complaints from their subject about the “large” quantity of food they were asked to eat. Little did the subjects realize that the high-fiber diets contained no more calories than low-fiber diet.

This is a clue that fiber creates a feeling of fullness. Nutritionists have long suspected that it does. In the stomach, fiber swells with water. This may help curb hunger.

Some scientists also believe that high-fiber foods help with weight control because they take longer to chew.

One thing is for sure: a high-fiber diet based on whole grains, fruits, and vegetables is likely to be nutritionally sound. That is more than can be said for so many of the “miracle” weight-loss diets that come along every year.

More Benefits of Fiber

Fiber is now known to benefit the following conditions:

1. Diverticulosis and diverticulitis
2. High blood cholesterol
3. Diabetes
4. It may also help prevent tooth decay!

Let’s take a closer look at these findings.

Diverticulosis is a common condition among older people. It refers to outpouchings of the intestines. Food can get caught in these pockets. Often the result is inflammation and pain.

Doctors used to treat this problem with a low-fiber diet. But much to their surprise, they have learned that a high-fiber diet usually gives much better results. In general, patients are asked to add wheat bran to their diets.

Dental researchers believe that whole grain foods may play a role in preventing tooth decay. Studies show that something in whole grains may protect the teeth from decay-producing acids in the mouth. The bacteria in the mouth produce these acids.

( The Next Fiber’s Benefit and How to Estimate Fiber Content )

If you are concerned about your iron intake, consider some of these sources:

* Lean meats and shellfish

* Whole grain or enriched cereals

* Dried apricots, prunes, or raisins

* Nuts and wheat germ

* Dried beans and peas

* Leafy green vegetables

Liver, especially pork liver, contains large amounts of iron. But it is also rich in cholesterol. Too many of us eat too much of cholesterol-containing foods. Egg yolk has a moderate iron content; it is high in cholesterol, too.

The iron in flesh foods, called heme iron, is best absorbed by the body. Yet studies have found no more iron-deficiency anemia among vegetarians than among meat eaters.

One possible explanation is vitamin C. It enhances absorption of the iron in foods. Vegetarians often consume more vitamin C than meat-eaters. The vitamin C may compensate for the absence of meat in their diets.

A Look at Lead

Lead has long been in the headlines. Lead poisoning has occurred too frequently among children – often from eating chips of old paint that contained lead.

Whatever lead also plays any role in the cancer process is an open question. Only a few studies have been done – mostly in animals. These studies suggest that large amounts of lead might increase the risk of kidney cancer. But this form of cancer is not very common. (I never forget my friend, a medical doctor, who died 4 years ago, at the age of 40, due to kidney cancer).

The committee on Diet, Nutrition, and Cancer declined to make any recommendations regarding lead.

Some Advice about Canned Foods

Lead remains a concern to health experts for other reasons. The chances of getting lead poisoning are not great, but the problems has yet to be eliminated in U.S. and other countries. Infants, children, and pregnant women are at greatest risk.

Scientists estimate that food accounts for 55 – 85 percent of our exposure to lead. The lead in canned foods can seep into the food itself. Public pressure and encouragement from the Food and Drug Administration (FDA) have led canners to reduce the lead content of food by almost 40 percent during the last 30 years.

Acidic foods packed in cans made with lead are the most likely to absorb this mineral. Fruits and fruit juices, including tomato products, fall into this category. If these foods are stored in the can after opening, the lead content can increase fivefold in less than a week.

Lead experts urge us not to store acidic foods in cans after opening. Transfer the food to a glass or plastic container. This precaution will go a long way to preventing unnecessary lead in the diet. Foods taste better, too, when this advice is followed.

Unfortunately, there is no easy way to tell whether a csn has been soldered with lead. Evaporated milk is usually packed in lead-soldered cans. Infant formulas are not. Processed meats are also usually packed in non-leaded cans.

There’s Much More to the Story

Though research has yet to find that lead or other minerals play a major role in cancer prevention, the story of nutrition and cancer is not yet over. We have looked at vitamins, minerals, fiber, and cancer inhibitors. but there’s more to come.

The Next story tells about the dietary change that may offer the biggest dividends of all.

Encouraged by reports linking the mineral to cancer protection, people are buying – and taking – selenium supplements. In some Asia countries, they call selenium as the king of anti-cancer substances.  But, a few words of caution are in order.

At high doses, selenium can cause health problems. Fatigue and irritability, as well as brittleness or loss of hair, have been seen in patients suffering from toxic amounts of selenium. A research scientist exposed to too much selenium developed bronchitis and skin problems.

How Much is Too Much?

According to the Food and Nutrition Board of the National Research Council, a long term intake of 2400 to 3000 micrograms of selenium per day would be expected to cause a toxic reaction.

It is very unlikely that the diet could provide such a high level of selenium. In fact, there is only recorded instance of selenium toxicity caused by food. It dates back about seventy five years and occurred among people living in an area of the country where the soil was unusually rich in this mineral.

To overdose on selenium, you would probably have to work with it or take supplements. In 1977, the Food and Nutrition Board (U.S.) advised:

There is no justification at this time for the use of selenium supplements by the general population. Should selenium supplements eventually be condidered desirable for those persons living in low-selenium areas, or for those consuming vegetarian diets, a daily supplement of 50 to 100 micrograms could probably be taken safely. (Emphasis added.)

Five years later, in 1982, the Committee on diet, Nutrition, and Cancer (U..S.) seemed to agree with the Food and Nutrition Board’s opinion. “Increasing the selenium intake to more than 200 micograms a day…….. by the use of supplements has not been shown to confer health benefits exceeding those derived from consumption of  a balanced diet,” said tyhe panel.

Selenium in Our Diet

It is not easy to list the selenium content of common foods. The amount of selenium in meat, for instance, can vary. It depends partly on the amount of the mineral in the animals’ diets.

The selenium content of the soil also varies throughout the regions of each country. The soil content, inturn, greatly affects the amount of selenium in grains. But most of us  now eat foods grown from many parts of our country; no longer do we eat only foods grown nearby. Furthermore, recently so many foods were imported from Asia and other countries.

As a result, nutritionosts rarely see signs of selenium deficiency among Americans. The average selenium intake in the United States, for instance, is 150 micrograms per day, which is considered more than enough  for most people.

Good sources of selenium are:

• Meat and seafood
• Grains, unless, grown in soil low in selenium
• Asparagus and mushrooms
• Garlic
• Meats and seafood are the richest source of this mineral.

Fruits and most vegetables contain little selenium. The selenium content of dairy products and eggs varies.

Can Iron Help, Too?

Adequate iron in the diet prevents a condition called Plummer-Vinson syndrome. This condition has been linked to increased risk of developing stomach cancer and cancer of the esophagus.

Probing these findings, scientists have found that iron deficiency allows bacteria to grow in the stomach. It is possible that these bacteria turn nitrites into the cancer causing substances called nitrosamines.

But, as is the case with selenium, there is still not much evidence to go on. It certainly makes sense, though, to eat iron-rich foods (unless your doctor has advised against it. Some people, though not many, have a disorder that causes them to retain too much iron).

Iron deficiency is not truly widespread in some countries. But many people, such in case of Americans, don’t get the RDA for iron. This hardly means that all of these people have iron deficiency. The RDA is set higher than about 96 % of us need. It is not a requirement, but rather a “better-safe-than-sorry” approach.

The Best Sources of Iron

If you are concerned about your iron intake, consider some of these sources:

• Lean meats and shellfish
• Whole grain or enriched cereals
• Dried apricots, prunes, or raisins
• Nuts and wheat germ
• Dried beans and peas
• Leafy green vegetables

(  Next Story, the Part III )

It is an alluring idea. Some have even proposed that the quick fix already does exist – in the form of a mineral called selenium.

But the wishful thinking is a little premature. There is some evidence that the minerals in our food play a role in preventing cancer. More research is needed, though, before we can draw any conclusions.

The Minerals in Food

Food contains a wide range of minerals. We need some of them in large amounts. Other minerals are required in very small amounts.

Nutritionists refer to the minerals needed in large amounts as major minerals. Those that we need in small amounts are known as trace minerals or trace elements.

The most important major minerals are:

• calcium
• magnesium
• sodium
• chloride
• phosphorous
• potassium

There are many trace minerals. Scientists know a great deal about some of them, and very little about others. Some of the trace minerals include:

• copper
• chromium
• fluorine
• iodine
• iron
• manganese
• molybdenum
• selenium
• zinc

When it comes to minerals and cancer, research has focused only on trace minerals. None of the major minerals have been the focus of cancer research.

Too Soon to Tell

Most cancer institutions and foundations, including Committee on Diet, Nutrition, and Cancer (U.S.), made no recommendation about minerals. In general, the scientists found too little evidence for making judgment.
Some of them cited selenium and iron as the best-studied minerals. But though they found evidence that selenium may protect both humans and animals against some forms of cancer, the evidence was ruled preliminary.
Similarly, they found evidence that an adequate iron intake protects both humans and animals against cancer in the upper part of the digestive tract. But this findings, too, were considered inconclusive.

In this case, the Committee on Diet, Nutrition, and Cancer said that no conclusions could be drawn at all about the role of the following minerals in cancer prevention:

• copper
• zinc
• molybdenum
• iodine
• arsenic
• cadmium
• lead

It may surprise you to read the committee’s conclusions about these last three minerals – arsenic, cadmium, and lead. You may be aware that these minerals have long been linked to excessive cancer rates among workers who are heavily exposed to them. But occupational exposure to these minerals is many times higher than the levels that occur in food. For this reason, too, the committee declined to make any judgments.

The Selenium Story

Chances are that you have heard reports about the ability of selenium to prevent cancer. A few enthused promoters have inspired some people to take selenium supplements as a preventive measure.

The evidence that selenium helps to prevent cancer is promising but far from final. Research has shown, for instance, that:

1. Areas of the world where selenium intake is high have lower cancer rates than countries where the diet is low in selenium.
2. Blood selenium levels are higher in healthy people than in cancer victims.
3. Selenium added to the diet or drinking water of laboratory animals helps to protect against cancer-causing chemicals.

One problem with these findings is clear. Scientists can rarely know whether a cancer patient always had a low blood level of selenium. It is possible that the disease, once developed, cause a normal selenium level to drop suddenly.
Some research has yielded opposite results, showing no relationship between the selenium in the blood and the risk of cancer. But on the whole, the research on this mineral must be considered promising.

Oddly enough, there were once concerns that selenium might promote cancer. These fear have not been supported by the most recent research.
But research has shown that selenium can be toxic in other ways. Scientists hardly want to advocate a measure that will help prevent one disease but cause others instead.

By the way, I would be very grateful if you have some latest valuable information regarding this subject, never hesitate to write down on the comment board below.

( Next Story, the Part II )

The cabbage family is not the only group of foods that has shown potential to block the cancer process. Other foods may also have this ability – and some may be even more potent than foods of the cabbage family.

But the evidence for these other foods is not as strong. Some foods have inhibited cancer in studies on animals, but studies with humans have yet to be done. Other foods have been studied in only one or two experiments – too few for judgment. This is why some health institution such as Committee on Diet, Nutrition, and Cancer limited its recommendations to the cabbage family.

Of the other foods that might also contain inhibitors, the evidence is best for citrus fruits. The beneficial effect of these foods has ranged from weak to potent in studies with animals.

As for other foods, the evidence is just beginning to come in. But for your information, I would like you to know some of the possibilities now under further study:

• Celery and spinach have shown slight but significant inhibiting ability.
• Soybeans and lima beans have also shown some potential.
• Grains and vegetable oils may contains a substance with moderate inhibiting power.
• Green coffee beans have shown a powerful inhibiting effect in early studies. But roasted and instant coffee have shown only a weak effect.

Remember: for some of these foods only several studies have been done. This is far too little work to justify changing your diet.

Some Unanswered Questions

Scientists are still a little cautious about the cancer inhibitors in food. They aren’t 100 percent convinced that these substances are only beneficial.

The Committee on Diet, Nutrition, and Cancer tells us that its matter of weighing the pluses and minuses. On the balance, the panel scientists agrees that the good points of the cabbage family vegetables outweigh the bad points.

What are the bad points? Mostly, they fall under the label of “uncertain effects.”

As noted earlier, inhibitors seem to activate an enzyme system that is thought to detoxify harmful chemicals. There is some concern that this very same enzyme system may also enhance the power of some chemicals. In other words, the enzyme system may have both good and bad effects.

Despite information on this subject is incomplete, still,  the scientists recommend that we eat citrus fruits, whole grains, and cabbage family vegetables. Obviously, the scientists think that the pluses here outweigh  the minuses.

But until this question is settled, it is best not to go all out with cabbage family vegetables. Eating them often – but not exclusively – is probably the best course of action. Including them in your diet once or twice a week is a cautious, moderate approach.

Putting It All Together

Up to this point, you have read a great deal about fruits, vegetables, and grains. It is fitting, I think, to take a broad look at these foods to see how they score when all protective factors are taken into account.

There are four factors to consider: vitamin A, vitamin C, insoluble fiber, and inhibitors. To take a simple approach to these four factors, I have devised a rating system.

I gave a food one point if it contains a moderate amount of vitamin A and two points for a high level. I used the same system for vitamin C and for insoluble fiber.

I then awarded two points to the four members of the cabbage family that appear to contain a cancer inhibitor other than vitamin A and C or fiber. I gave one point to the other foods that might have a cancer inhibitor.

The Top-Scoring Cancer-Blocking Foods

When all the points were tallied, broccoli and brussels sprouts topped the list.

They were followed by some vegetables that many people eat little of: collards, kale, kohlrabi, mustard greens, and rutabagas.

But in third place were some familiar faces: oranges, grapefruit, cabbage, cauliflower, lima beans, and spinach. Watercress also rated with this group.

Chances are that you like some of these foods. Pick the ones you like best, and continue to enjoy them.